Table 4. Haematological toxicities. Common toxicity criteria grades 3 and 4.

	Dose level 1	Dose level 2	Dose level 3	Dose level 4
	3 patients	3 patients	16 patients	6 patients
Anaemia	0	0	0	0
Leucopenia	0	0	1a	0
Lymphocytopenia	1	3	2b	1a
Neutropenia	0	0	1a	0
Thrombocytopenia	0	0	4c	4

^aTemozolomide alone.

^bTemozolomide alone, one patient.

^cTemozolomide alone, three patients.