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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Curr Opin Microbiol. 2008 Apr 8;11(2):153–160. doi: 10.1016/j.mib.2008.02.013

Figure 2. Genetic synthetic interaction network of Tor1.

Figure 2

A, graphical representation of genes (grouped in functional categories) that when mutated in combination with tor1 result in synthetic lethal or reduced fitness defects. B, schematic representation of the distinct functional categories involved in protein sorting and vacuolar function, that exhibit synthetic interactions with tor1. Mutation of the genes shown in bold confer rapamycin hypersensitivity as demonstrated by two recent studies [46*,47].