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OT-I T cell proliferation and CD44 up-regulation occur after transfer into T- and T/B- deficient, nonirradiated hosts. OT-I.PL CD8+ T cells were transferred into unmanipulated B6 (A and E), B6 RAG0/0 (B and F), or thymectomized, T cell-depleted B6 (C and G) recipients for 9 days. Expression levels of CFSE (A-C) and staining for CD44 (E-G) are shown for the lymph node population gated on donor cells. CD44 expression by the preinjection donor population (D) is shown for comparison.
