Table 2. Rate ratios (95% confidence intervals) for systolic and diastolic blood pressure in relation to site-specific cancer mortality.

	All-cancers		Lung		Oesophagus		Stomach		Pancreas		Colon		Rectum
	(2226 deaths)		(658 deaths)		(77 deaths)		(157 deaths)		(107 deaths)		(198 deaths)		(71 deaths)
	Age-adjusted	Multiply- adjusteda	Age-adjusted	Multiply-adjusted	Age-adjusted	Multiply-adjusted	Age-adjusted	Multiply-adjusted	Age-adjusted	Multiply-adjusted	Age-adjusted	Multiply-adjusted	Age-adjusted	Multiply-adjusted
Systolic blood pressure (mmHg)
Tertile 3	0.96	0.98	0.76	0.82	1.23	1.14	1.21	1.18	0.73	0.72	0.81	0.78	1.27	1.20
(⩾143)	(0.87, 1.07)	(0.89, 1.10)	(0.62, 0.92)	(0.67, 1.00)	(0.70, 2.13)	(0.64, 2.01)	(0.82, 1.77)	(0.80, 1.76)	(0.45, 1.18)	(0.44, 1.19)	(0.57, 1.14)	(0.55, 1.12)	(0.71, 2.27)	(0.66, 2.17)
Tertile 2	0.94	0.97	0.86	0.94	1.00	0.98	0.90	0.91	0.86	0.87	0.80	0.80	1.03	1.00
(126–142)	(0.85, 1.05)	(0.88, 1.07)	(0.72, 1.04)	(0.78, 1.13)	(0.57, 1.75)	(0.56, 1.72)	(0.60, 1.35)	(0.61, 1.37)	(0.55, 1.35)	(0.55, 1.36)	(0.57, 1.12)	(0.57, 1.12)	(0.57, 1.87)	(0.55, 1.81)
Tertile 1	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0
(⩽125)
Per 10 mmHg	1.00	1.00	0.95	0.97	1.00	0.98	1.06	1.05	0.94	0.94	0.96	0.95	1.04	1.03
increase	(0.97, 1.02)	(0.98, 1.02)	(0.92, 0.99)	(0.93, 1.01)	(0.90, 1.12)	(0.88, 1.11)	(0.98, 1.14)	(0.98, 1.14)	(0.85, 1.04)	(0.85, 1.04)	(0.89, 1.03)	(0.88, 1.02)	(0.93, 1.16)	(0.91, 1.16)
P for trend	0.62	0.89	0.011	0.15	0.94	0.79	0.15	0.18	0.21	0.22	0.24	0.17	0.54	0.65
Diastolic blood pressure (mmHg)
Tertile 3	0.91	0.99	0.63	0.79	1.30	1.24	1.11	1.14	0.63	0.64	0.98	0.94	1.88	1.84
(⩾89)	(0.82, 1.01)	(0.89, 1.10)	(0.52, 0.76)	(0.65, 0.97)	(0.71, 2.38)	(0.66, 2.32)	(0.76, 1.62)	(0.76, 1.70)	(0.39, 1.02)	(0.39, 1.05)	(0.70, 1.38)	(0.65, 1.34)	(1.06, 3.34)	(1.01, 3.34)
Tertile 2	0.86	0.92	0.72	0.85	1.64	1.66	0.90	0.94	0.72	0.74	0.88	0.86	0.96	0.95
(78–88)	(0.78, 0.96)	(0.83, 1.02)	(0.60, 0.86)	(0.71, 1.02)	(0.94, 2.88)	(0.94, 2.93)	(0.61, 1.34)	(0.64, 1.40)	(0.46, 1.13)	(0.47, 1.17)	(0.63, 1.24)	(0.61, 1.22)	(0.50, 1.83)	(0.50, 1.82)
Tertile 1	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0
(⩽77)
Per 10 mmHg	0.99	1.02	0.90	0.98	1.01	0.99	1.03	1.04	0.86	0.86	0.96	0.95	1.19	1.19
increase	(0.96, 1.02)	(0.99, 1.06)	(0.85, 0.95)	(0.92, 1.04)	(0.85, 1.20)	(0.83, 1.18)	(0.92, 1.16)	(0.92, 1.18)	(0.74, 1.00)	(0.73, 1.01)	(0.87, 1.07)	(0.85, 1.06)	(1.01, 1.40)	(1.00, 1.41)
P for trend	0.50	0.24	0.0004	0.46	0.88	0.89	0.61	0.52	0.05	0.06	0.51	0.36	0.04	0.05

^aAdjustment for confounding (age, employment grade, smoking status, blood pressure-lowering medication, marital status, disease at study entry) and mediating (body mass index, triceps skinfold thickness, FEV₁, cholesterol) variables.