Table 4. Multivariate analyses of relative risks for all cancers and selected cancer sites following organ transplantation.
|
All cancers |
Nonmelanoma skin cancer |
Lip cancer |
Non-Hodgkin's lymphoma |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Obs | RR | 95% CI | Obs | RR | 95% CI | Obs | RR | 95% CI | Obs | RR | 95% CI | |
| Follow-up (years) | ||||||||||||
| <1 | 93 | 1 | ref | 10 | 1 | ref | 0 | 0 | na | 16 | 1 | ref |
| 1–4 | 248 | 0.9 | 0.7–1.1 | 86 | 2.3 | 1.2–4.5 | 14 | 1 | ref | 11 | 0.2 | 0.1–0.5 |
| 5–9 | 200 | 1.0 | 0.8–1.3 | 92 | 2.8 | 1.4–5.3 | 19 | 1.6 | 0.8–3.2 | 11 | 0.3 | 0.2–0.8 |
| 10+ | 151 | 0.9 | 0.7–1.2 | 90 | 2.4 | 1.2–4.7 | 7 | 0.6 | 0.3–1.6 | 7 | 0.3 | 0.1–0.7 |
| Age at transplantation (years) | ||||||||||||
| <39 | 155 | 2.5 | 2.0–3.1 | 71 | 3.8 | 2.7–5.4 | 4 | 1.6 | 0.5–5.3 | 9 | 4.8 | 1.6–14.7 |
| 40–49 | 158 | 1.4 | 1.1–1.8 | 51 | 1.5 | 1.0–2.2 | 17 | 2.8 | 1.2–6.3 | 14 | 3.5 | 1.2–9.8 |
| 50–59 | 229 | 1.2 | 0.9–1.4 | 90 | 1.4 | 1.0–1.9 | 10 | 1.0 | 0.9–1.4 | 17 | 2.1 | 0.8–5.9 |
| 60+ | 150 | 1 | ref | 66 | 1 | ref | 9 | 1 | ref | 5 | 1 | ref |
| Gender | ||||||||||||
| Male | 442 | 1.5 | 1.3–1.8 | 194 | 0.9 | 0.7–1.2 | 29 | 0.5 | 0.3–1.1 | 31 | 1.0 | 0.5–1.8 |
| Female | 250 | 1 | ref | 84 | 1 | ref | 11 | 1 | ref | 14 | 1 | ref |
| Transplanted organ | ||||||||||||
| Kidney | 639 | 1 | ref | 267 | 1 | ref | 39 | 1 | ref | 27 | 1 | ref |
| Other | 53 | 1.4 | 1.0–1.8 | 11 | 0.7 | 0.4–1.3 | 1 | 0.5 | 0.1–3.5 | 18 | 8.4 | 4.3–16 |
Results shown as relative risks (RRs) and 95% confidence intervals (CI) after mutual adjustment for follow-up time, age at transplantation, gender and transplanted organ.