Table 1. Patient characteristics.
Cisplatin–gemcitabine |
Epirubicin–gemcitabine |
||||
---|---|---|---|---|---|
No. | % | No. | % | P | |
Patients entered | 119 | 50 | 121 | 50 | ns |
Sex | ns | ||||
Male | 94 | 79 | 85 | 70 | |
Female | 25 | 21 | 36 | 30 | |
Age, years | |||||
Median | 60 | 60 | |||
Range | 29–80 | 32–76 | ns | ||
Stage | ns | ||||
IIIa | 8 | 7 | 8 | 7 | |
IIIb | 43 | 36 | 44 | 36 | |
IV | 68 | 57 | 69 | 57 | |
Performance status | ns | ||||
0 | 36 | 30 | 37 | 31 | |
1 | 66 | 55 | 73 | 60 | |
2 | 17 | 14 | 11 | 9 | |
Histology | ns | ||||
Squamous cell carinoma | 41 | 35 | 32 | 26 | |
Adenocarcinoma | 41 | 35 | 50 | 41 | |
Large cell carcinoma | 36 | 30 | 38 | 31 | |
Other | 1 | 1 | 1 | 1 | |
Weight loss (last 3 months) | ns | ||||
<5% | 82 | 69 | 80 | 66 | |
⩾5% | 37 | 31 | 41 | 34 | |
Liver metastases | ns | ||||
Absent | 109 | 92 | 111 | 92 | |
Present | 10 | 8 | 10 | 8 |
ns=Not significant.