Table 3. Worst nonhaematologic CTC toxicity grade per patient.

	Cisplatin–gemcitabine		Epirubicin–gemcitabine
Toxicity	No.	%	No.	%	P
Bilirubin					ns
1	5	4	10	10
2	0	0	1	1
3/4	0	0	2	2
ASAT					<0.01
1	31	27	43	40
2	0	0	8	7
3/4	0	0	4	4
ALAT					<0.01
1	50	44	46	43
2	12	10	27	25
3/4	2	2	14	13
Creatinine					<0.01
1	53	45	10	9
2	9	8	4	4
3/4	0	0	0	0
Mucositis					<0.01
1	15	13	23	20
2	7	6	46	40
3/4	0	0	14	12
Nausea					<0.01
1	36	31	46	40
2	51	44	27	24
3/4	5	4	1	1
Vomiting					<0.01
1	37	32	28	25
2	27	23	11	10
3/4	2	2	1	1
Diarrhoea					ns
1	6	5	15	13
2	4	3	2	2
3/4	3	3	1	1
Fever					<0.01
1	11	9	22	19
2	2	2	12	10
3/4	1	1	3	3
Infections					ns
1	0	0	1	1
2	2	2	3	3
3/4	9	8	13	11
Skin reactions					ns
1	9	8	14	12
2	7	6	1	1
3/4	1	1	2	2
Sensory neuropathy					<0.01
1	16	14	2	2
2	7	6	1	1
3/4	0	0	0	0
Motoric neuropathy					ns
1	0	0	0	0
2	2	2	2	2
3/4	1	1	1	1
Anorexia					ns
1	50	43	46	40
2	27	23	38	33
3/4	2	2	0	0
Fatigue					<0.05
1	41	35	22	19
2	54	46	57	50
3/4	5	4	5	4

ns=Not significant.