Table 1a. The HER2/chromosome 17 ratio, HER2 copy number, chromosome 17 copy number, IHC score and time to progression in months for all 26 tumour pairs.

Patient number	HER2/chromosome 17 ratio	Chromosome 17 copy number	HER2 copy number	IHC score	Time to progression (months)
1a	1.06	2.75	2.89	‘3’	13
1b	1.25	3.48	4.33	‘3’
2a	1	1.74	1.73	‘3’	62
2b	1.17	1.93	2.25	‘2’
3a	1.21	3.86	4.68	‘2’	9
3b	1.16	3.41	4.03	‘1’
4a	1.13	2.33	2.6	‘3’	3
4b	1.51	3.19	4.97	‘3’
5a	1.02	1.83	1.87	‘3’	38
5b	1.06	1.81	1.9	‘0’
6a	1.09	1.98	2.14	‘3’	2
6b	1.5	2.13	3.17	‘3’
7a	1.09	3.49	3.83	‘3’	3
7b	0.98	2.96	2.93	‘2’
8a	0.82	3.28	2.61	‘3’	19
8b	1	8.48	8.5	‘3’
9a	0.95	2.22	2.09	‘2’	32
9b	1.07	2.08	2.21	‘1’
10a	1.06	2.77	2.9	‘2’	10
10b	0.83	2.51	2	‘0’
11a	0.92	2.35	2.15	‘3’	4
11b	0.96	2.63	2.49	‘3’
12a	0.91	2.7	2.47	‘3’	42
12b	0.98	3.15	3.07	‘3’
13a	0.78	3.26	2.5	‘3’	12
13b	0.88	2.78	2.4	‘3’
14a	0.96	3.39	3.24	‘3’	17
14b	0.9	3.43	3.08	‘3’
15a	2.18	2.9	6.33	‘3’	6
15b	2.09	3.01	6.2	‘3’
16a	1.14	2.43	2.74	‘1’	5
16b	1.48	4.7	7.04	‘0’
17a	8.07	2.3	18.3	‘3’	26
17b	1.45	2.26	3.17	‘0’
18a	0.96	1.91	1.82	‘0’	3
18b	2.02	1.62	3.2	‘0’
19a	1.11	2.26	2.54	‘0’	3
19b	1.06	3.89	4.07	‘0’
20a	0.98	1.97	1.93	‘0’	90
20b	1.33	3.43	2.58	‘0’
21a	1.02	1.91	1.94	‘0’	10
21b	0.99	2.01	1.98	‘0’
22a	1.04	2.13	2.21	‘2’	55
22b	1.06	3.69	3.79	‘3’
23a	1.05	2.2	2.33	‘3’	6
23b	1.06	2.16	2.29	‘3’
24a	1.07	3.62	3.8	‘3’	15
24b	0.96	2.98	2.86	‘0’
25a	0.95	1.84	1.75	‘0’	31
25b	0.69	5.5	3.83	‘0’