Skip to main content
. 2003 Oct 14;89(8):1581–1589. doi: 10.1038/sj.bjc.6601300

Figure 4.

Figure 4

Permeation of drug-sensitive and -resistant TS by fluorescent allocrites of P-gp. TSWT (panels AC) and TSAdr (panels DF) were incubated in the presence of 2.5 μM BODIPY-taxol (A, D), 5 μM rhodamine-123 (B, E) or 5 μM calcein-AM (C, F) for 60 min. Optical sectioning of TS (d=300–400 μM) was achieved by confocal fluorescence microscopy and the images shown were taken at a depth of 60 μM from the tissue periphery. The white bars correspond to 100 μM.