. 2003 Oct 14;89(8):1566–1573. doi: 10.1038/sj.bjc.6601317

Table 1. IC₅₀ in AD and AI cells in response to the treatment of either paclitaxel or vinorelbine alone for 7 days, or paclitaxel for 3 days followed by vinorelbine for additional 4 days.

Cell lines	Treatment	IC₅₀ (nM)	P-value
AD	Paclitaxel (T)	0.035±0.005	Tvs N, P<0.01
AD	NVB (N)	0.310±0.061	T vs T+N, P<0.001
AD	Paclitaxel followed by T + N	0.0015±0.0007	N vs T+N, P<0.001
AI	Paclitaxel (T)	0.650±0.140	T vs N, P>0.05
AI	NVB (N)	0.590±0.091	T vs T+N, P<0.001
AI	Paclitaxel followed by T + N	0.110±0.003	N vs T+N, P<0.001

The IC₅₀ was calculated and statistically analysed between the treatments using PC program Sigma Plot from three separate experiments. T=treated with paclitaxel, N=treated with vinorelbine (NVB), and T+N=treated with paclitaxel followed by paclitaxel plus NVB as described in ‘Materials and Methods’.

Table 1. IC50 in AD and AI cells in response to the treatment of either paclitaxel or vinorelbine alone for 7 days, or paclitaxel for 3 days followed by vinorelbine for additional 4 days.

Table 1. IC₅₀ in AD and AI cells in response to the treatment of either paclitaxel or vinorelbine alone for 7 days, or paclitaxel for 3 days followed by vinorelbine for additional 4 days.