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. 2003 Jul 29;89(3):573–576. doi: 10.1038/sj.bjc.6601134

Table 1. Summary of the ability of a range of human and murine normal and malignant cell lines to utilise citrulline, argininosuccinate and arginine.

          Type C
Cell designation Species Origin Type Aa Type B AS+ AS−
JMF9 Human Skin fibroblast       +
             
A375 Human Melanoma   +    
MEWO Human Melanoma   +    
G361 Human Melanoma +      
B16F10b Murine Melanoma       +
             
HL428 Human Leukaemia       +
JURKAT Human Leukaemia       +
L1210 Murine Leukaemia       +
             
HeLa Human Cervical carcinoma       +
SAos-2 Human Osteogenic sarcoma   +    
CHO Chinese hamster Ovary +      
a

This refers to the absence of growth when twice the concentration of citrulline was added instead of arginine.

b

Non-human lines shaded. Type A: grow only when arginine is present; Type B: grow on arginine or argininosuccinate, but not citrulline; Type C/As+: grow on citrulline and argininosuccinate; Type C/As−: grow on citrulline, but cannot grow on argininosuccinate.