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. 2003 Jul 29;89(3):482–486. doi: 10.1038/sj.bjc.6601052

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Copyright © 2003 Cancer Research UK

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Suspected relapses and true relapses according to modality of detection. In 109 cases, an abnormality prompted an intensification of follow-up (suspected relapse) which led to the detection of Hodgkin's relapse (true relapse) in 22 cases. Suspected relapses were attributed to the ‘patient’ (46 cases, yielding 10 relapses) when triggered by a patient-reported symptom or sign; to the ‘physician’ (28 cases, yielding four relapses) when triggered by the physical examination; to ‘radiological’ (31 cases, yielding six relapses) when triggered by an abnormality on a CXR, CT or other radiological investigation; or to ‘laboratory’ (four cases, yielding two relapses) when brought on by an abnormal CBC. A hierarchical classification system was employed when multiple follow-up modalities suggested a possible relapse (see Materials and Methods).