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. 2003 Jul 29;89(3):585–592. doi: 10.1038/sj.bjc.6601131

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Copyright © 2003 Cancer Research UK

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Impact of ZD1839 on key pathways regulated by EGFR signalling. (A) ZD1839 (6 μM, IC₅₀ value) diminished MAP kinase phosphorylation. (B) ZD1839 (6 μM, IC₅₀ value) diminished AKT phosphorylation. ^*P<0.05 vs control, bars indicate standard deviation from the mean of three separate experiments.