Table 1. High level infiltration of immune cells and histopathological findings in gallbladder cancer.
Variables | High CD4+ TILs (%) | High CD8+ TILs (%) | High NKC infiltration (%) | High DC infiltration (%) |
---|---|---|---|---|
Depth of invasion | ||||
pT1 (n=9) | 5 (55.6) | 5 (55.6) | 3 (33.3) | 6 (66.7) |
pT2 (n=22) | 16 (72.7) | 11 (50.0) | 7 (31.8) | 12 (54.5) |
pT3 (n=9) | 1 (11.1) | 1 (11.1) | 4 (44.4) | 2 (22.2) |
pT4 (n=5) | 1 (20.0) | 0 (0.0) | 1 (20.0) | 2 (40.0) |
Lymph node metastasis | ||||
pN0 (n=27) | 12 (44.4) | 16 (59.3) | 10 (37.0) | 17 (63.0) |
pN1 (n=6) | 1 (16.7) | 1 (16.7) | 2 (33.3) | 1 (16.7) |
pN2 (n=12) | 4 (33.3) | 6 (50.0) | 3 (25.0) | 4 (33.3) |
Histopathological grading | ||||
G1 (n=27) | 12 (44.4) | 17 (63.0) | 9 (33.3) | 16 (59.3) |
G2 (n=15) | 3 (33.3) | 4 (26.7) | 6 (40.0) | 4 (26.7) |
G3 (n=3) | 2 (66.7) | 2 (66.7) | 0 (0.0) | 2 (66.7) |
P-stage grouping | ||||
I (n=9) | 5 (55.6) | 5 (55.6) | 3 (33.3) | 6 (66.7) |
II (n=15) | 11 (73.3) | 7 (46.7) | 6 (40.0) | 10 (66.7) |
III (n=5) | 1 (20.0) | 1 (20.0) | 2 (40.0) | 1 (20.0) |
IV (n=16) | 6 (37.5) | 4 (25.0) | 4 (25.0) | 5 (31.3) |
TILs=tumour-infiltrating lymphocytes; NKC=natural killer cell; DC=dendritic cell.