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. 2003 Oct 28;89(9):1736–1742. doi: 10.1038/sj.bjc.6601331

Table 1. High level infiltration of immune cells and histopathological findings in gallbladder cancer.

Variables High CD4+ TILs (%) High CD8+ TILs (%) High NKC infiltration (%) High DC infiltration (%)
Depth of invasion
 pT1 (n=9) 5 (55.6) 5 (55.6) 3 (33.3) 6 (66.7)
 pT2 (n=22) 16 (72.7) 11 (50.0) 7 (31.8) 12 (54.5)
 pT3 (n=9) 1 (11.1) 1 (11.1) 4 (44.4) 2 (22.2)
 pT4 (n=5) 1 (20.0) 0 (0.0) 1 (20.0) 2 (40.0)
         
Lymph node metastasis
 pN0 (n=27) 12 (44.4) 16 (59.3) 10 (37.0) 17 (63.0)
 pN1 (n=6) 1 (16.7) 1 (16.7) 2 (33.3) 1 (16.7)
 pN2 (n=12) 4 (33.3) 6 (50.0) 3 (25.0) 4 (33.3)
         
Histopathological grading
 G1 (n=27) 12 (44.4) 17 (63.0) 9 (33.3) 16 (59.3)
 G2 (n=15) 3 (33.3) 4 (26.7) 6 (40.0) 4 (26.7)
 G3 (n=3) 2 (66.7) 2 (66.7) 0 (0.0) 2 (66.7)
         
P-stage grouping
 I (n=9) 5 (55.6) 5 (55.6) 3 (33.3) 6 (66.7)
 II (n=15) 11 (73.3) 7 (46.7) 6 (40.0) 10 (66.7)
 III (n=5) 1 (20.0) 1 (20.0) 2 (40.0) 1 (20.0)
 IV (n=16) 6 (37.5) 4 (25.0) 4 (25.0) 5 (31.3)

TILs=tumour-infiltrating lymphocytes; NKC=natural killer cell; DC=dendritic cell.