Table 3. Correlation between immune cells and TNM classification, tumour differentiation, and stage grouping.
| CD4+TILS | CD8+TILs | NKCs | DCs | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Variables | Total (n=45) | Low/high | Pa | Low/high | Pa | Low/high | Pa | Low/high | Pa |
| pTb | |||||||||
| 1, 2 | 31 | 10/21 | 0.0009 | 16/15 | 0.0044 | 21/10 | >0.9999* | 13/18 | 0.0669 |
| 3, 4 | 14 | 12/2 | 13/1 | 9/5 | 10/4 | ||||
| pNc | |||||||||
| 0 | 27 | 11/16 | 0.1805 | 15/12 | 0.2586 | 17/10 | 0.5186 | 10/17 | 0.0207 |
| 1, 2 | 18 | 11/7 | 13/5 | 13/5 | 13/5 | ||||
| pMd | |||||||||
| 0 | 45 | 22/23 | – | 28/17 | – | 30/15 | – | 23/22 | – |
| 1 | 0 | 0/0 | 0/0 | 0/0 | 0/0 | ||||
| Ge | |||||||||
| 1 | 27 | 10/17 | 0.0514 | 15/12 | 0.2586 | 18/9 | >0.9999 | 11/16 | 0.0883 |
| 2, 3 | 18 | 12/6 | 13/5 | 12/6 | 12/6 | ||||
| P-stage | |||||||||
| I, II | 24 | 8/16 | 0.0256 | 12/12 | 0.0706 | 15/9 | 0.5262 | 8/16 | 0.0108 |
| III, IV | 21 | 14/7 | 16/5 | 15/6 | 15/6 | ||||
a
χ2 test except for *Fisher's exact test.
b
depth of invasion;
c
lymph node metastasis;
d
distant metastasis;
e
histopathological grading. TILs=tumour-infiltrating lymphocytes; NKCs=natural killer cells; DCs=dendritic cells. The underlined numbers=significant.