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. 2003 Oct 28;89(9):1766–1775. doi: 10.1038/sj.bjc.6601346

Figure 6.

Figure 6

Effect of gefitinib on MAP kinase activity in CM cells. CM cells were treated with 10 μM gefitinib for 0–48 h. At the indicated time points, the amount of phosphorylation of ERK1/2 and p38MAP kinases was analysed by Western blotting. (A) Gefitinib induced a time-dependent decrease in phosphorylated ERK1/2. (B) By contrast, no change in p38 MAPK phosphorylation was observed upon treatment with gefitinib.