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. 2003 Oct 28;89(9):1638–1644. doi: 10.1038/sj.bjc.6601319

Table 5. Relative risk of soft-tissue and bone cancer, colorectal cancer, and breast cancer as a function of the cumulative 131I activity administered 2 years or more before the diagnosis of SPMs.

  Number of SPMs and RRa (95% CI)
Amount of 131I (GBq) Soft-tissue and bone cancer Colorectal cancer Breast cancer
⩽0.2 5 1 (ref) 32 1 (ref) 74 1 (ref)
[0.2–3.6] 5 2.9 (0.8–10.7) 12 0.9 (0.5–1.8) 23 0.9 (0.5–1.4)
[3.7–7.3] 4 3.4 (0.8–13.3) 13 1.1 (0.6–2.2) 19 0.6 (0.3–1.0)
[7.4–14.7] 3 7.7 (1.5–33.3) 8 2.5 (1.0–5.5) 9 1.0 (0.4–1.9)
⩾14.8 2 13.0 (1.7–67.1) 4 3.2 (0.9–8.7) 3 0.9 (0.2–2.5)
a

Relative risk adjusted on external radiotherapy and stratified on study group.