Table 4. Haematologic toxicities (phase II portion) (n=42).

	No. of patients with grade
	0	1	2	3	4	% of toxicities grade ⩾3
Leukopenia	0	2	10	24	6	71
Granulocytopenia	2	3	12	18	7	60
Anaemia	1	12	19	9	1	24
Thrombocytopenia	35	2	2	3	0	7

Haematologic toxicity was assessed and graded using ECOG common toxicity criteria (Oken et al, 1982).