Table 2. Haematological and nonhaematological toxicity in the phase I study.

		Neutropenia		Thrombocytopenia		Oesophagitis		Pneumonitis
Carboplatin dose level (mg m−2)	No. of patients	Grade 3	Grade 4	Grade 3	Grade 4	Grade 2	Grade 3	Grade 2	Grade 3
20	3	1	0	0	0	0	0	0	0
25	3	2	0	1	0	1	0	0	0
30	4	2	0	1	0	0	0	0	0
35	6	4	2	4	0	0	0	0	0
40	6	2	4	4	0	2	0	0	0