Table 3. Frequency of hr-HPV genotypes in patients with ACIS with coexisting CIN compared with patients with ACIS without coexisting CIN.
| hr-HPV genotype | ACIS with CIN n=49 | ACIS without CIN n=47 | Significance |
|---|---|---|---|
| 16 | 19 (39%) | 20 (43%) | NS |
| 18 | 23 (47%) | 18 (38%) | NS |
| 31 | 0 (0%) | 0 (0%) | NS |
| 45 | 5 (10%) | 2 (4%) | NS |
| Other | 2 (4%) | 1 (2%) | NS |
| Multiple | 2 (4%) | 3 (6%) | NS |
| Total hr-HPV positive | 47 (96%) | 38 (81%) | χ2=6.07, P<0.02 |
| hr-HPV negative | 2 (4%) | 9 (19%) | χ2=6.63, P<0.01 |
ACIS=adenocarcinoma in situ; hr-HPV= high-risk human papillomavirus; CIN=cervical intraepithelial neoplasia; NS=not significant.