Table 2.

High H2A.Z expression is an independent marker associated with decreased patient survival

Variable	Univariate analysis		Multivariate analysis
	Hazard ratio (95% CI)	P-value	Hazard ratio (95% CI)	P-value
Nodal status		<0.0001		<0.0001
Positive	2.31 (1.82–2.96)		2.03 (1.52–2.73)
Nuclear grade		0.0018		0.38
High (3/3)	1.52 (1.17–1.96)		1.14 (0.84–1.53)
H2A.Z expression		0.0004		0.027
High	1.73 (1.29–2.31)		1.44 (1.04–1.97)
E2 receptor status		0.060		0.63
Negative (0/3)	1.25 (1.00–1.59)		1.07 (0.81–1.42)
Progesterone receptor status		0.042		0.20
Negative (0/3)	1.28 (1.01–1.62)		1.20 (0.91–1.59)
HER2/neu status		0.19		0.052
Positive (2–3/3)	1.23 (0.90–1.65)		1.45 (1.00–2.06)
Tumor size (per cm)	1.15 (1.10–1.20)	<0.0001	1.10 (1.04–1.16)	0.0010

CI, confidence interval.

Univariate and multivariate analyses of overall breast cancer patient survival were performed based on Cox proportional-hazards regression models. Hazard ratios with 95% CIs are indicated. Statistically significant observations (P<0.05) are in boldface.