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Bax antisense (as Bax) but not scrambled oligodeoxynucleotides (sc Bax) reduce Bax protein expression in neutrophils. (A) Flow cytometry. Control and inflammatory diseases neutrophils (cystic fibrosis) were cultured in the presence of as Bax or sc Bax for 48 h. (B) Immunocytochemistry. (×1,000.) Control neutrophils were cultured in the presence of GM-CSF, sc Bax, and as Bax for 48 h. Data are representative of at least three independent experiments.
