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Rpd3p binding in wild-type and histone acetylation in rpd3Δ cells in AT-rich and GC-rich isochors. (a) Average levels of Rpd3p binding to each of the six groups of genes with increasing GC content. Rpd3p binding data are from Humphrey et al. [42]. (b) Average change in H4 acetylation of the upstream region of each of the six groups of genes with increasing GC content. Acetylation data were obtained by Bernstein et al. [30].
