Table 5.

Effects of RNAi and cadmium on C. elegans reproduction

Target gene	CGC gene name	Reproduction rate (minus cadmium)*	Reproduction rate (plus cadmium)*	Diff. of medians	P value†
T10B9.1	cyp-13A4	0.92, 0.92, 0.88, 0.96, 0.87	0.57, 0.59, 0.61, 0.79, 0.72	0.31	0.008
F28D1.3	thn-1	1.04, 1.02, 1.14, 1.03	0.89, 0.86, 0.92, 0.92	0.13	0.029
F35E8.11	cdr-1	1.01, 1.02, 0.94, 0.95, 1.19, 1.04	1.38, 1.21, 0.88, 0.79, 0.80, 0.84	0.15	0.394
Y39B6A.24		1.10, 1.03, 1.09	1.01, 1.21, 1.03	0.06	0.700
T26H2.5		0.88, 0.99, 0.81	0.74, 0.95, 1.00	-0.07	1.000
K11G9.6	mtl-1	0.85, 1.13, 0.99, 0.90, 1.07	0.97, 1.16, 1.12, 1.08, 1.12	-0.13	0.222
T27F6.2	clec-12	1.10, 0.90, 1.00, 1.03, 0.64, 0.90	1.05, 1.32, 1.42, 0.94, 1.32, 0.83	-0.24	0.180
C17H1.4		0.87, 0.89, 1.13	0.91, 1.06, 1.75	-0.15	0.686
C08E3.10		0.94, 0.93, 1.03	1.39, 1.24, 1.26	-0.32	0.100
M88.1	ugt-62	0.93, 1.03, 0.99, 1.05, 0.98, 0.89	1.08, 0.94, 1.34, 0.83, 0.95, 0.88	0.04	0.818
Y39E4A.2	ttm-1	0.73, 0.88, 1.05, 0.91, 0.94, 0.83, 1.01, 1.03	0.86, 0.82, 1.12, 0.91, 0.94, 0.93, 0.83, 0.85	0.04	0.721
F42C5.3		1.01, 0.94, 1.02, 1.12, 1.05, 0.99	1.06, 1.19, 1.10, 0.94, 0.91, 0.90	0.02	0.818
F53H2.1		1.06, 0.94, 1.00, 1.20, 0.95, 0.93	1.27, 1.30, 1.05, 1.05, 1.07, 0.96	-0.08	0.132
F09B9.1		0.76, 1.04, 1.06, 0.89, 1.13, 0.96, 1.01	1.04, 0.73, 0.95, 0.72, 0.88, 0.85, 0.92	0.13	0.073
Y46G5A.24		1.10, 0.94, 1.12	0.98, 0.87, 0.80	0.23	0.200

*The reproduction rate was calculated by comparing the number of offspring with the targeted gene knocked-down by RNAi to those without RNAi in the same cadmium-treatment group during a two day reproduction period after nematodes reached L4 stage of development. ^†Wilcoxon Rank-sum tests were applied for significance tests.