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. 2007 Jun 19;8(6):R118. doi: 10.1186/gb-2007-8-6-r118

Table 2.

Summary of SNPs within ANC sequences and power CNC sequences associated to differential gene expression

Population Sequence Number of tested ANC/CNC sequences Number of SNPs Number of probes tested Number of associations Number of significant ANC/CNC sequence to gene associations Number of significant ANC/CNC sequences of those tested

0.01 0.001 0.0001 0.01 0.001 0.0001
CEU ANC 387 555 8,673 23,330 77 9 0 59 (15%) 9 (2%) 0 (0%)
Power CNC 6,232 8,388 14,906 350,309 181 36 18 149 (2%) 33 (1%) 17 (0%)
CHB ANC 356 499 8,092 21,291 83 13 0 56 (16%) 11 (3%) 0 (0%)
Power CNC 5,737 7,579 14,893 317,518 202 41 15 159 (3%) 39 (1%) 15 (0%)
CHB and JPT ANC 342 466 7,919 20,163 109 11 1 59 (17%) 9 (3%) 1 (0%)
Power CNC 5,474 7,162 14,852 301,636 203 12 1 149 (3%) 12 (0 1 (0%)
JPT ANC 355 490 8,197 21,166 88 12 0 59 (17%) 11 (3%) 0 (0%)
Power CNC 5,674 7,531 14,852 315,476 241 48 20 194 (3%) 42 (1%) 19 (0%)
YRI ANC 391 583 9,118 24,310 113 15 2 64 (16%) 15 (4%) 2 (1%)
Power CNC 6,724 9,218 14,908 381,407 196 32 15 173 (3%) 30 (0%) 14 (0%)

Presented are results for four populations: the Yoruba people from Ibadan Nigeria (YRI), US residents with Northern and Western European ancestry (CEU), Han Chinese from Beijing (CHB), and Japanese from Tokyo (JPT). ANC, accelerated noncoding; CNC, conserved noncoding; SNP, single nucleotide polymorphism.