Skip to main content
. 2008 Apr 18;15(Pt 3):204–207. doi: 10.1107/S0909049507064229

Table 3. P2 buried surface area/activity relationship (generic formula 9).

Compd P2 Ki* SA SA Rel. Ki* SA Rel. Ki* exp. Ki* ratio exp./SA
7 Pro 5000 25 0 1 1 1.0
8 Leu 1000 63 38 19 5 0.3
9 DMCP 14 83 58 86 360 4.1
10 DCCP 19 70 45 32 260 8.1
11 DFCP 140 51 26 7 36 4.8