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. 2008 Mar 19;15(5):885–887. doi: 10.1128/CVI.00035-08

TABLE 1.

Plasma concentrations of cytokines in PUUV-infected females and males during the acute phase of HFRSa

Cytokine Mean plasma concn ± SD (pg/ml) in:
P value
Females (n = 20) Males (n = 19)
IL-1β 4.1 ± 4.7 2.1 ± 1.4 0.35
IL-1RA 471 ± 453 1,160 ± 1,560 0.07
IL-2 25.1 ± 38.3 7.8 ± 11.8 0.11
IL-4 3.3 ± 5.8 0.5 ± 1.2 0.20
IL-5 4.5 ± 8.5 3.3 ± 7.5 0.39
IL-6 22.1 ± 27.8 19.0 ± 18.2 0.76
IL-7 3.9 ± 3.3 3.4 ± 3.2 0.48
IL-8 14.2 ± 17.3 48.3 ± 85.8 0.02
IL-9 367 ± 653 141 ± 207 0.02
IL-10 22.2 ± 22.5 47.9 ± 55.9 0.18
IL-12 (p70) 24.1 ± 46.1 17.0 ± 67.1 0.13
IL-13 3.1 ± 6.0 1.0 ± 1.9 0.37
IL-15 5.7 ± 8.6 3.5 ± 5.4 0.66
IL-17 27.1 ± 62.3 1.0 ± 4.2 0.11
Eotaxin 74.5 ± 41.1 66.9 ± 22.4 0.94
FGF-2 66.9 ± 71.7 13.4 ± 16.2 0.004
G-CSF 57.9 ± 186 13.8 ± 15.1 0.77
GM-CSF 54.9 ± 82.5 10.9 ± 16.2 0.006
IFN-γ 62.6 ± 89.7 201 ± 699 0.71
IP-10 2,880 ± 5,430 10,700 ± 15,600 0.007
MCP-1 233 ± 360 302 ± 256 0.07
MIP-1α 3.3 ± 8.9 0.0 ± 0.0 0.42
MIP-1β 83.3 ± 56.2 124 ± 84.3 0.07
PDGF-BB 626 ± 1390 549 ± 856 0.37
RANTES 5,710 ± 12,500 10,400 ± 16,900 0.80
TNF 18.1 ± 33.9 5.4 ± 12.5 0.17
VEGF 38.8 ± 27.2 41.0 ± 26.6 0.70
a

Cytokines for which significant sex differences were observed are indicated in bold. P values were determined with the Mann-Whitney U test.