TABLE 1.
Cytokine | Mean plasma concn ± SD (pg/ml) in:
|
P value | |
---|---|---|---|
Females (n = 20) | Males (n = 19) | ||
IL-1β | 4.1 ± 4.7 | 2.1 ± 1.4 | 0.35 |
IL-1RA | 471 ± 453 | 1,160 ± 1,560 | 0.07 |
IL-2 | 25.1 ± 38.3 | 7.8 ± 11.8 | 0.11 |
IL-4 | 3.3 ± 5.8 | 0.5 ± 1.2 | 0.20 |
IL-5 | 4.5 ± 8.5 | 3.3 ± 7.5 | 0.39 |
IL-6 | 22.1 ± 27.8 | 19.0 ± 18.2 | 0.76 |
IL-7 | 3.9 ± 3.3 | 3.4 ± 3.2 | 0.48 |
IL-8 | 14.2 ± 17.3 | 48.3 ± 85.8 | 0.02 |
IL-9 | 367 ± 653 | 141 ± 207 | 0.02 |
IL-10 | 22.2 ± 22.5 | 47.9 ± 55.9 | 0.18 |
IL-12 (p70) | 24.1 ± 46.1 | 17.0 ± 67.1 | 0.13 |
IL-13 | 3.1 ± 6.0 | 1.0 ± 1.9 | 0.37 |
IL-15 | 5.7 ± 8.6 | 3.5 ± 5.4 | 0.66 |
IL-17 | 27.1 ± 62.3 | 1.0 ± 4.2 | 0.11 |
Eotaxin | 74.5 ± 41.1 | 66.9 ± 22.4 | 0.94 |
FGF-2 | 66.9 ± 71.7 | 13.4 ± 16.2 | 0.004 |
G-CSF | 57.9 ± 186 | 13.8 ± 15.1 | 0.77 |
GM-CSF | 54.9 ± 82.5 | 10.9 ± 16.2 | 0.006 |
IFN-γ | 62.6 ± 89.7 | 201 ± 699 | 0.71 |
IP-10 | 2,880 ± 5,430 | 10,700 ± 15,600 | 0.007 |
MCP-1 | 233 ± 360 | 302 ± 256 | 0.07 |
MIP-1α | 3.3 ± 8.9 | 0.0 ± 0.0 | 0.42 |
MIP-1β | 83.3 ± 56.2 | 124 ± 84.3 | 0.07 |
PDGF-BB | 626 ± 1390 | 549 ± 856 | 0.37 |
RANTES | 5,710 ± 12,500 | 10,400 ± 16,900 | 0.80 |
TNF | 18.1 ± 33.9 | 5.4 ± 12.5 | 0.17 |
VEGF | 38.8 ± 27.2 | 41.0 ± 26.6 | 0.70 |
Cytokines for which significant sex differences were observed are indicated in bold. P values were determined with the Mann-Whitney U test.