Reactivities toward the CCR5 peptide in cervicovaginal secretion samples from 18 HIV-seronegative women (HIV−) and 10 HIV-1-infected women (HIV+). Autoantibody activities toward the CCR5 peptide were detected as described in Materials and Methods. Each point represents the mean OD of duplicate assays. The results are expressed in μg/ml. According to the threshold of the indirect ELISA used (50 μg/ml), all CVL fluid samples except those from women 5, 6, 13, 16, 17, and 18 contained relevant amounts of CCR5-specific antibodies. *, women whose cervicovaginal secretion samples contained traces of semen.