FIG. 7.

OVCAR-3 cells were cultured with increasing concentrations of abrin (0.2 to 200 ng/ml) in the presence of 2.5 μg of MAb D6F10 or MAb F5B10/ml for a period of 8 h and monitored for protein synthesis as described in the legend to Fig. 5. “Control” denotes cells cultured without abrin or MAbs. In the case of MAb F5B10, data for 0.2 ng of abrin/ml alone are shown here. The experiment was carried out at least three times. Representative data are presented. DMEM, Dulbecco's modified Eagle's medium.