FIG. 2.

Prominent IFN-γ production in splenocytes of M. vaccae-treated TB mice stimulated in vitro with CWS compared to that in splenocytes of M. vaccae-treated TB mice stimulated with M. vaccae. Concentrations were measured in culture supernatants by ELISA. The data are shown as mean values plus standard deviations obtained from four mice per group. TB, mice infected with M. tuberculosis; TB + MV 10⁷, mice infected with M. tuberculosis and treated with 10⁷ cells of M. vaccae. NA, nonantigen; ConA, concanavalin A; MV, heat-killed M. vaccae; L, lipids. *, P < 0.05; Mann-Whitney rank sum test.