Table 6.
Mean levels of plasma Se measurements according to the presence of gastric precancerous lesions (MAG/IM/DYS) by risk area in males from Nariño, Colombia (2006)
|
Gastric cancer risk area |
||||||
|---|---|---|---|---|---|---|
| Variables | Low riska n=26 | High risk n=44 | ||||
| Normal/NAG n=16 | MAG/IM/DYS n=10 | Two-tailed P valueb | Normal/NAG n=16 | MAG/IM/DYS n=28 | Two-tailed P valueb | |
| Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |||
| Plasma selenium (ug/dl) | 12.1 (1.5) | 11.5 (0.8) | 0.240 | 10.6 (0.9) | 10.7 (1.3) | 0.834 |
| Sepp1 (ug/ml) | 5.4 (1.1) | 4.7 (1.3) | 0.155 | 5.6 (0.7) | 5.9 (1.0) | 0.293 |
| GPx activity (nmol/min/ml plasma) | 110.3 (15) | 111.7 (20) | 0.620 | 104.9 (15) | 108.6 (18) | 0.490 |
| Other selenium pool | 4.8 (1.8) | 5.0 (1.6) | 0.865 | 3.1 (0.8) | 2.8 (1.) | 0.353 |
Abbreviations: SD: standard deviation; NAG, non-atrophic gastritis; MAG, multifocal atrophic gastritis; IM, intestinal metaplasia; DYS, dysplasia; Sepp1, selenoprotein-P; GPx, extracellular glutathione peroxidase
a
A case classified as gastritis, NOS (in which atrophy could not be assessed) was not included in this comparison
b
P-values for difference from t-test.