TABLE 1.
Antibiotic susceptibility of B. anthracis strains from Switzerland
| Strain | Origin/date of isolation | MIC (μg/ml)a
|
Reference(s) or source | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GEN | AMI | STR | ERY | CLI | SYN | TET | CHL | ENR | CEP | VAN | LNZ | PEN | AMC | NIT | SXT | |||
| JF3783 | Human anthrax, wool processing industry outbreak | ≤2 | ≤16 | ≤4 | 1 | ≤0.5 | 2 | ≤1 | ≤4 | ≤0.25 | ≤2 | ≤1 | 1 | ≤0.12 | ≤2/1 | ≤16 | 1/19 | Reference 10 and this study |
| JF3784 | Air filter, wool processing industry outbreak | ≤2 | ≤16 | ≤4 | 1 | ≤0.5 | 2 | ≤1 | ≤4 | ≤0.25 | ≤2 | ≤1 | 1 | ≤0.12 | ≤2/1 | ≤16 | 2/38 | Reference 10 and this study |
| JF3785 | Goat hair, wool processing industry outbreak | ≤2 | ≤16 | ≤4 | 0.5 | ≤0.5 | 1 | ≤1 | ≤4 | ≤0.25 | ≤2 | ≤1 | 1 | ≤0.12 | ≤2/1 | ≤16 | 1/19 | Reference 10 and this study |
| JF3786 | Goat hair, wool processing industry outbreak | ≤2 | ≤16 | ≤4 | 1 | ≤0.5 | 1 | ≤1 | ≤4 | ≤0.25 | ≤2 | ≤1 | 1 | ≤0.12 | ≤2/1 | ≤16 | 1/19 | Reference 10 and this study |
| JF3787 | Goat hair, wool processing industry outbreak | ≤2 | ≤16 | ≤4 | 1 | ≤0.5 | 2 | ≤1 | ≤4 | ≤0.25 | ≤2 | ≤1 | 1 | ≤0.12 | ≤2/1 | ≤16 | 1/19 | Reference 10 and this study |
| JF3788 | Human anthrax, wool processing industry outbreak | ≤2 | ≤16 | ≤4 | 1 | ≤0.5 | 2 | ≤1 | ≤4 | ≤0.25 | ≤2 | ≤1 | 1 | ≤0.12 | ≤2/1 | ≤16 | 1/19 | Reference 10 and this study |
| JF3852 | Cattle, Bern, Switzerland, 1953 | ≤2 | ≤16 | ≤4 | 2 | ≤0.5 | 1 | ≤1 | ≤4 | ≤0.25 | ≤2 | ≤1 | 1 | ≤0.12 | ≤2/1 | ≤16 | >8/152 | This study |
| JF3853 | Cattle, central Switzerland, 1952 | ≤2 | ≤16 | ≤4 | 1 | ≤0.5 | 2 | ≤1 | ≤4 | ≤0.25 | ≤2 | 2 | 1 | ≤0.12 | ≤2/1 | ≤16 | 1/19 | This study |
| JF3854 | Cattle, central Switzerland, 1957 | ≤2 | ≤16 | ≤4 | 1 | ≤0.5 | 1 | ≤1 | ≤4 | ≤0.25 | ≤2 | ≤1 | 1 | ≤0.12 | ≤2/1 | ≤16 | 2/38 | This study |
| JF3887 | Cattle, eastern Switzerland, 1960 | ≤2 | ≤16 | ≤4 | 1 | ≤0.5 | 1 | ≤1 | ≤4 | ≤0.25 | ≤2 | ≤1 | 1 | ≤0.12 | ≤2/1 | ≤16 | 4/76 | This study |
| JF3888 | Cattle, eastern Switzerland, 1962 | ≤2 | ≤16 | ≤4 | 1 | ≤0.5 | 1 | ≤1 | ≤4 | ≤0.25 | ≤2 | ≤1 | 1 | ≤0.12 | ≤2/1 | ≤16 | 4/76 | This study |
| JF3889 | Eastern Switzerland, 1981 | ≤2 | ≤16 | ≤4 | 1 | ≤0.5 | 2 | ≤1 | ≤4 | ≤0.25 | ≤2 | ≤1 | 1 | ≤0.12 | ≤2/1 | ≤16 | 1/19 | This study |
| NCTC8234 | Vaccine strain, Sterne 34F2 | ≤2 | ≤16 | ≤4 | 1 | ≤0.5 | 1 | ≤1 | ≤4 | ≤0.25 | ≤2 | ≤1 | 1 | ≤0.12 | ≤2/1 | ≤16 | 4/76 | NCTC |
a
AMI, amikacin; AMC, amoxicillin-clavulanic acid (ratio 2:1); CEP, cephalothin; CHL, chloramphenicol; CLI, clindamycin; ENR, enrofloxacin; ERY, erythromycin; GEN, gentamicin; LZD, linezolid; NIT, nitrofurantoin; PEN, penicillin; STR, streptomycin; SXT, trimethoprim-sulfamethoxazole (ratio 1:19); SYN, quinupristin-dalfopristin; TET, tetracycline; VAN, vancomycin.