TABLE 1.
Presence of folate biosynthesis genes in the genome of L. reuteri JCM1112 as determined by homology searches with L. plantarum WCFS1
L. plantarum WCFS1 open reading frame | Gene | Length of protein (amino acids)a | Assigned function |
L. reuteri JCM1112 orthologue
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Open reading frame | Length of protein (amino acids)a | % Identity
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Amino acid | Nucleotide | ||||||
lp3299 | folB | 122 | Dihydroneopterin aldolase (EC 4.1.2.25) | Lreu1280 | 111 | 48 | 58 |
lp3298 | folK | 170 | 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) | Lreu1279 | 170 | 43 | 55 |
lp3297 | folE | 189 | GTP cyclohydrolase I (EC 3.5.4.16) | Lreu1278 | 192 | 57 | 59 |
lp3296 | folC2 | 454 | Folylpolyglutamate synthase (EC 6.3.2.17)/dihydrofolate synthase (EC 6.3.2.12) | Lreu1277 | 419 | 38 | 47 |
lp3295 | xtp2 | 195 | XTP pyrophosphatase (EC 3.6.1.-) | Lreu1276 | 195 | 35 | 48 |
lp3294 | folP | 263 | Dihydropteroate synthase (EC 2.5.1.15) | Lreu1275 | 387 | 37 | 39 |
Length based on the number of amino acid residues predicted in the gene product.