FIG. 1.

Proposed structural domains of Efg1p and corresponding phenotypes. Top, proposed structural domains of Efg1p. The conserved APSES domain consists of the bHLH region (hatched) and adjacent regions (gray). Polyglutamine stretches (Q) are indicated, as well as a low-complexity region containing a stretch of alanines (A) and prolines (P) (checkered). Deletions D1 to D11 are marked by amino acid positions within and framing the deletions. Two Efg1 regions predicted by the GlobPlot program (http://globplot.embl.de) to form globular domains are shown (A). Sequences essential for the wild-type phenotypes listed (B, C, and D) are indicated by black bars; sequences partially required are shown as gray bars.