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Size of the tumors derived from wild-type J1 cells and Parp-deficient ES clones in nude mice. Three weeks after s.c. injection of ES cells at each flank, resected tumors were weighed. The observed number of tumors were: J1, n = 10; clone 210, n = 9; clone 226, n = 11; clone 210–58, n = 9; clone 226–47, n = 10. Bar indicates the average size of the tumors.
