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. 2008 Mar 28;190(11):3835–3850. doi: 10.1128/JB.00167-08

FIG. 1.

FIG. 1.

Structural organization of FnBPA from S. aureus 8325-4 and diagrammatic illustration of plasmid constructs lacking regions of FnBPA. Regions B, C, and D (tandem repeats 1 to 11) are required for fibronectin binding. Region A (comprising the subdomains N1, N2, and N3) binds fibrinogen and elastin. The LPXTG motif, required for sortase-mediated anchoring of the protein to the cell wall peptidoglycan, is indicated. The secretory signal sequence (S), wall-spanning (W), and membrane-spanning (M) domains are indicated.