FIG. 5.

Anaplerotic role for MCM revealed by growth of M. tuberculosis on valerate with vitamin B₁₂ supplementation. (A) Growth of H37Rv on valerate in the presence of 3NP with (□) or without (▪) vitamin B₁₂ supplementation versus growth of the ΔprpDC mutant on vitamin B₁₂-supplemented valerate with (▵) or without (▴) 3NP. (B) Growth of H37Rv on vitamin B₁₂-supplemented valerate with (□) or without (▪) 3NP. Data are OD₆₀₀ for a single representative experiment from three independent biological replicates.