TABLE 3.
Resolution by PCR/sequencing for discordant positive/negative samples
Assay | True HR HPV-positive results
|
False HR HPV-positive results
|
HPV-negative results
|
||||
---|---|---|---|---|---|---|---|
No. of HR DNA-positive results (types identified) | No. of samples showing type 66 cross-reactivity with HR probes | No. of HPV DNA-negative results | No. of samples showing HR probe cross-reactivity with LR types (types identified) | Total no. of false- positive results | No. of true-negative results | No. of false-negative results (type) | |
Invader HPV | 7 (16, 45, 56, 59, 66) | 0 | 3 | 6 (6, 67, 73, 84, 91) | 8 | 38 | 30 (66) |
HC2 | 15 (16, 31, 35, 52, 53, 56, 58, 59, 68) | 15 | 13 | 25 (6, 30, 42, 43, 53, 61, 72, 73, 84, 87, 91) | 38 | 7 | 9 |