TABLE 1.
Comparison between carriers of SCV and of normal colony types of P. aeruginosa and S. aureus
Clinical parametera | Patients infected with P. aeruginosa
|
Patients infected with S. aureus
|
||||
---|---|---|---|---|---|---|
SCV | Normal colony type | P | SCV | Normal colony type | P | |
Total no. | 9 | 53 | 8 | 32 | ||
Age (yr) | 19 (12-23) | 16 (1-37) | 0.09 | 16.5 (3-36) | 8 (1-40) | 0.04 |
Age at colonization with P. aeruginosa (yr) | 7.5 (0.6-11.5) | 5.0 (0.2-28.1) | 0.45 | |||
Age at colonization with S. aureus (yr) | 4.1 (0.5-16) | 4.2 (0.3-32.2) | 0.35 | |||
Duration of colonization with P. aeruginosa (yr) | 9.9 (5.5-18.4) | 7.9 (0.1-23.4) | 0.13 | 9.04 (0.3-12.9) | 3.88 (0.25-16.2)b | 0.08 |
Duration of colonization with S. aureus (yr) | 14.9 (2.5-20.0) | 2.4 (0.1-20.1) | 0.007 | |||
Underweight (% of predicted weight) (<18 yr old) | 14.0 (12.5-16.0) | 2.7 (0-21.1) | 0.02 | 6.8 (0-12.2) | 1 (0-20.1) | 0.4 |
Body-mass index (>18 yr old) | 17.9 (13.6-20.0) | 19.2 (16.6-21.9) | 0.04 | 19.3 (16.6-21.9) | 19.4 (18.2-21.1) | 0.9 |
% of predicted FEV1 | 39.0 (21-90) | 65.5 (24-125) | 0.01 | 57.5 (21-109) | 92.0 (32-122) | 0.01 |
PaO2 (mm Hg) | 64.0 (47.7-72.0) | 71.5 (54.6-89.0) | 0.004 | 66.8 (48.5-85.0) | 74.0 (62-85) | 0.07 |
Pretreatment with: | ||||||
i.v. aminoglycosides | ||||||
No. (%) | 7 (77.7) | 34 (64.1) | 0.42 | 5 (62.5) | 6 (18.1) | 0.01 |
Duration (wks) | 5 (0-11) | 2 (0-16) | 0.16 | 3 (0-16) | 0 (0-4) | 0.02 |
Topical aminoglycosides | ||||||
No. (%) | 7 (77.7) | 26 (49.0) | 0.11 | |||
Duration (wks) | 31 (0-135) | 0 (0-138) | 0.33 | |||
Cotrimoxazole | ||||||
No. (%) | 7 (87.5) | 11 (33.3) | 0.01 | |||
Duration (wks) | 42.5 (0-138) | 0 (0-49) | 0.001 | |||
Ciprofloxacin | ||||||
No. (%) | 8 (88.8) | 41 (77.3) | 0.43 | |||
Duration (wks) | 27 (0-49) | 6 (0-94) | 0.07 |
Due to the small number of patients with SCV, summary measures are given as median (range). i.v., intravenous.
n = 24. Eight of 32 carriers of the normal phenotype of S. aureus were not coinfected with P. aeruginosa.