FIG. 4.

HIV-1 can infect primary mouse macrophages from emerin and LAP2α knockout mice. Infection efficiency of HIV/VSV-G was examined in macrophages from emerin knockout, LAP2α knockout, and emerin and LAP2α double knockout mice compared to wild-type littermate controls. At 60 h postinfection, the cells were stained for the F4/80 macrophage-specific marker. The percent infectivity represents the percentage of GFP-positive cells in the F4/80-positive population. Each data set represents the mean of four separate wells of infected cells, and error bars indicate standard deviations.