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Paxillin domains. Diagram of paxillin mutants indicating the location of five LD motifs (peptide motifs with the consensus sequence LXXLLXXL) and four zinc-finger LIM domains. Y31, 33, and Y118 are tyrosine phosphorylation sites. Binding partners for the LD motifs, tyrosine phosphorylation sites, and functions ascribed to the LIM domains are from Brown and Turner (6). “F.A. localization” refers to focal adhesion localization, a function ascribed to LIM domains 2 and 3 (6).
