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CCR5 expression on CD4+ T cells of uninfected baby (n = 12; aged >6 months) versus adult (n = 23) mandrills (a) and representative flow cytometry plots of CCR5 expression on CD4+ T cells in a young AGM versus that in an adult AGM (b). Significantly lower CCR5 expression was observed with young versus adult animals. Note that CCR5 expression is already low in African NHPs compared to that in rhesus macaques or in humans (45).
