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. 2008 Mar 19;82(11):5450–5459. doi: 10.1128/JVI.01952-07

FIG. 3.

FIG. 3.

Cell markers on Vpu-specific IFN-γ-expressing lymphocytes. Whole blood from subject 26 was pulsed with the Vpu epitope. Gated lymphocytes are shown in all plots. The proportions of cells expressing IFN-γ are shown in the relevant quadrant. (A) IFN-γ-expressing lymphocytes all expressed CD2. CD3-negative gated lymphocytes are shown. (B) Only a proportion of the IFN-γ-expressing lymphocytes expressed CD56. CD2+ CD3− gated lymphocytes are shown. Percentages in the upper-right and upper-left quadrants show the proportion of CD56+ and CD56− cells that express IFN-γ, respectively. Overall ∼50% of IFN-γ-expressing cells are CD56+. (C and D) IFN-γ-expressing lymphocytes did not express intracellular TCRαβ or TCRγδ. Gated lymphocytes are shown. (E and F) There was no expression of the CD3 complex by IFN-γ-expressing lymphocytes, but intracellular expression of the CD3 epsilon subunit was detected. Gated lymphocytes are shown.