Figure 4.
Application to synthetic data. For illustration, we applied the different methods to a large set of synthetic examples. Left: Original gene expression bias profile. Middle: Results for proposed method. Right: Results for CGHseg. As evident, the proposed method better succeeds in recovering the true expression bias profile, especially under rough conditions. The example shown was generated using π = 0.2, but agreeing results were obtained for π = 0.0 to 0.5. In this test, Tμ = 0.5·SNR (similar results for other reasonable values).