Table 1. Breast cancer risk in South Asian first-generation migrants in England by sociodeomographic, reproductive and other variables: univariable analysis.
Category per unit increase | ORa | 95% CIb | P-value | |
---|---|---|---|---|
Socio-demographic characteristics | ||||
Age on arrival in UK | Per 5 years | 1.00 | 0.98, 1.02 | 0.77 |
Migrated via East Africa | Yes vs no | 1.07 | 0.76, 1.51 | 0.70 |
Years of education | 0 | 1 | — | — |
1–7 | 1.44 | 0.80, 2.59 | 0.23 | |
8–13 | 2.18 | 1.24, 3.83 | 0.01 | |
⩾14 | 2.10 | 1.14, 3.87 | 0.02 | |
Social class | Nonmanual vs manual | 1.64 | 1.16, 2.33 | 0.01 |
Reproductive factors | ||||
Age at menarche (years) | Per year | 0.92 | 0.83, 1.02 | 0.10 |
Age at first birth (years) | <20 | 1 | — | — |
20–24 | 0.97 | 0.61, 1.55 | 0.91 | |
25–29 | 1.68 | 1.02, 2.77 | 0.04 | |
30+ | 1.49 | 0.77, 2.90 | 0.24 | |
Nulliparous | 1.38 | 0.64, 2.96 | 0.42 | |
Parity | 1–2 | 1 | — | — |
3–4 | 1.09 | 0.75, 1.59 | 0.64 | |
5–7 | 0.72 | 0.43, 1.22 | 0.22 | |
⩾8 | 0.44 | 0.12, 1.62 | 0.22 | |
Nulliparous | 1.11 | 0.55, 2.24 | 0.77 | |
Breast feedingc | Ever vs never | 0.70 | 0.47, 1.06 | 0.09 |
Duration of breast feeding | <6 months | 1 | — | — |
6–11 months | 1.27 | 0.69, 2.34 | 0.45 | |
12–23 months | 0.90 | 0.50, 1.62 | 0.74 | |
24–47 months | 1.14 | 0.63, 2.07 | 0.66 | |
⩾48 months | 0.91 | 0.48, 1.74 | 0.77 | |
Never | 1.50 | 0.92, 2.46 | 0.11 | |
Menopausal status | Post vs pre | 1.45 | 0.92, 2.30 | 0.11 |
Median age at menopaused | Per year | 1.03 | 0.99, 1.08 | 0.14 |
Familial factors | ||||
Family history of breast cancer | Yes vs no | 1.92 | 0.94, 3.91 | 0.07 |
Parental consanguinity | Yes vs no | 1.31 | 0.73, 2.35 | 0.37 |
Environmental factors | ||||
Adult height | Per 5 cm | 1.05 | 0.91, 1.22 | 0.49 |
Leg length | Per 5 cm | 0.94 | 0.80, 1.10 | 0.43 |
Waist : hip ratio | Per 10% | 1.05 | 0.88, 1.26 | 0.57 |
Waist circumference | Per 10 cm | 1.19 | 1.03, 1.39 | 0.02 |
BMIe at interview | Per 3 kg m−2 | 1.08 | 0.97, 1.19 | 0.15 |
METf score at age 12 years | Per 20% | 0.99 | 0.95, 1.04 | 0.78 |
METf score at age 30 years | Per 20% | 0.97 | 0.94, 1.01 | 0.20 |
Total energy | Per 500 kcal | 1.04 | 0.89, 1.23 | 0.61 |
NSPg per 1000 kcal | Per 2 g/1000 kcal | 0.84 | 0.73, 0.97 | 0.02 |
% energy from fat | Per 5% | 0.92 | 0.80, 1.05 | 0.22 |
OR=odds ratio (estimated from a conditional logistic regression model hence controlled for age and GP).
CI=confidence interval.
Among parous women.
Among postmenopausal women.
BMI=body mass index.
MET=metabolic equivalent score per week.
NSP=nonstarch polysaccharides.