Table 1. Patient characteristics.

					Polyp count		Polyps studied
Patients	Age (years)	Sex	APC mutation	Colectomy/intact colon	Baseline	6 months	Baseline	After sulindac
I	32	F	Not tested	IRA	19	3a	2	1
II	42	F	Codon 423	IRA	47	6a	2	6
III	52	F	Not tested	IRA	10	0	3	2b
IV	25	F	Codon 1061	IRA	7	0	1	2b
V	23	F	Segments 2–3c	IRA	10	3	1	1

^aComplete response after 10 months treatment with sulindac.

^bStudied after 4 months treatment with sulindac.

^cAssessed with protein truncation test, mutation between codons 1099 and 1217 (overlapping part of segments 2 and 3 of APC protein). Listed are age, sex, mutational status, surgical status, polyp count before and after 6 months sulindac and numbers of polyps studied.

F=female; IRA=ileorectal anastomosis; APC=Adenomatous polyposis coli.