Figure 6.

Flow cytometric analysis of induction of multiple cell-cycle checkpoint delays by the combination of β-lapachone and taxol. DU145 cells were treated with vehicle control for 24 h (A); treated with β-lapachone at 4 μM for 4 h and incubated in drug-free medium for 20 h (B); treated with taxol at 0.2 μM for 4 h and incubated in drug-free medium for 20 h (C); and treated with β-lapachone at 4 μM plus taxol at 0.2 μM for 4 h and incubated in drug-free medium for 20 h (D). Data represent one of three independent experiments.