Table 2.

Phenotype of C57BL/6 DIO mice

	Normal diet controls	DIO mice
Body weight (g)	28.7 ± 0.3	44.6 ± 0.6**
Blood
Glucose (mg/dL)	121 ± 3	160 ± 6*
HbA1c (%)	3.6 ± 0.2	3.5 ± 0.3
Serum
Glucose (mg/dL)	225 ± 15**	344 ± 22*
Insulin (ng/ml)	0.45 ± 0.06	5.07 ± 1.03**
Total cholesterol (mg/dL)	67.0 ± 3.3	223.0 ± 3.1**
Triglycerides (mg/dL)	93.0 ± 14.6	138.0 ± 9.8*
FFA (mEq/L)	0.35 ± 0.03	0.47 ± 0.02*
IL-6 (pg/ml)	191.2 ± 86.7	243.2 ± 144.7
TNFα(pg/ml)	24.0 ± 1.1	35.6 ± 2.4*
Corticosterone (ng/ml)	310 ± 30	380 ± 86
ACTH (ng/ml)	2.3 ± 0.2	3.3 ± 1.0

* p < 0.05 vs lean litter mates. **p < 0.01 vs lean littermates.