Laser-Doppler flow (±SEM) measured as a percent of baseline over lateral cortex in groups with halothane (A, B) and isoflurane (C, D) anesthesia. Panels A and C show measurements made during the first and second 5-minute MCAO of the IPC stimulus or equivalent times in sham groups. Panels C and D show measurements made at 5 and 10 minutes of the test MCAO conducted in mice with no prior surgery (naïve), prior anesthesia alone, sham surgery, or IPC at either 24, 48, 72, or 96 hours before the test MCAO.