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. Author manuscript; available in PMC: 2008 Jun 6.
Published in final edited form as: Oncogene. 2003 May;22(19):2950–2959. doi: 10.1038/sj.onc.1206423

Figure 6. Constitutive Mcl-1 expression prevents from apoptosis induced by IL-6 starvation starvation.

Figure 6

A: Parental XG-6 cells, XG-6GFP or XG6Mcl-1 cells were starved of IL-6 for 1 hour and cultured without cytokine or with 2 ng/mL IL-6. At various days of culture, cells were harvested and apoptotic cells were detected with annexin-V staining. Results are those of one experiment representative of five.

B: The experiment described in A was performed on five occasions with XG-1 and XG-6 cells. Results are the mean values ± SD of apoptotic cells (expressed as the percentage of the maximum observed with XG-6 or XG-1 cells cultured without IL-6) on day 3 of culture. The statistical significance was determined using a Student t test for pairs.